--- title: [TileDB Tech Talk] How TileDB Scales Federated Queries for BeginNGS description: Discover how TileDB's federated query technology enhances newborn genomic screening, enabling secure data sharing and revolutionizing rare disease detection while ensuring patient privacy. image: https://events.tiledb.com/hubfs/TileDB-webinar-April2025-thumb.jpg --- [![TileDB-Tech-Talk](https://events.tiledb.com/hs-fs/hubfs/TileDB-Tech-Talk-full-logo-h.png?width=220&height=52&name=TileDB-Tech-Talk-full-logo-h.png "TileDB-Tech-Talk")](https://tiledb.com) ## The webinar has been completed! Please provide your details to access the recording. ## APRIL 17, 2025  |  1:00-2:00 PM EST # Turning the Dials on Newborn Genomic Screening: # How TileDB Scales Federated Queries for  ![BeginNGS-w](https://events.tiledb.com/hs-fs/hubfs/BeginNGS-w.png?width=230&height=51&name=BeginNGS-w.png "BeginNGS-w") ![Jeremy Leipzig](https://events.tiledb.com/hs-fs/hubfs/Jeremy-Leipzig-circle.png?width=170&height=187&name=Jeremy-Leipzig-circle.png "Jeremy Leipzig") #### SPEAKER #### Jeremy Leipzig Senior Product Manager, TileDB ![Chase Christensen](https://events.tiledb.com/hs-fs/hubfs/Chase-Christensen-circle.png?width=170&height=187&name=Chase-Christensen-circle.png "Chase Christensen") #### SPEAKER #### Chase Christensen Staff Solutions Engineer, TileDB ## Register Now! Rare genetic conditions affect 300 million people globally and are leading causes of child mortality in high-income countries. The BeginNGS platform addresses this by enabling genetic screening of newborns hours after birth, combining human expertise with machine learning to interpret disease risk from genomic data. While data sharing between hospitals is crucial for scaling this life-saving screening worldwide, it raises significant privacy concerns. This Tech Talk explores how TileDB's federated query technology allows researchers to compare genetic information across institutions without transferring sensitive patient data, revolutionizing rare disease detection while maintaining privacy compliance. ![TileDB-Tech-Tech](https://events.tiledb.com/hs-fs/hubfs/TileDB-Tech-Tech-mark-blue2.png?width=55&height=63&name=TileDB-Tech-Tech-mark-blue2.png "TileDB-Tech-Tech") ## A preview of what you’ll learn in this TileDB Tech Talk ### Challenges in Scaling Newborn Genomic Screening An overview of the limitations in current variant warehouse solutions and the need for efficient, privacy-preserving data sharing in newborn screening. ### Expanding the BeginNGS Consortium The rationale behind expanding the BeginNGS network to include more pediatric and healthy adult populations, enhancing the accuracy and impact of rare disease detection. ### Federated Queries for Secure Data Sharing A deep dive into how TileDB’s federated query technology enables flexible, real-time genomic queries across institutions—without exposing sensitive patient data. ## TileDB - Designed for Discovery TileDB is foundational software designed by scientists for scientific discovery. TileDB structures all data types, including data that does not fit into relational databases designed for structured tabular data. Built on a powerful shape-shifting array database, TileDB handles the complexities of non-traditional “unstructured” multimodal data, such as genomic variants, bulk and single-cell transcriptomics, proteomics and, biomedical imaging, as well as the frontier data of the future. Used by science and data teams within big pharma and biotechs to power their multiomics FAIR data platforms, TileDB is the destination for scientific breakthroughs where frontier multimodal data is driving drug discovery. ## Speaker ![Seth Shelnutt](https://events.tiledb.com/hs-fs/hubfs/Seth_Shelnutt_white.png?width=163&height=172&name=Seth_Shelnutt_white.png "Seth Shelnutt") #### Seth Shelnutt Chief Technical Officer ### EXPLORE OUR CUSTOMER CASE STUDIES --- [![Quest Diagnostics](https://events.tiledb.com/hs-fs/hubfs/QuestDiagnostics-h.png?width=150&height=48&name=QuestDiagnostics-h.png "Quest Diagnostics")](https://tiledb.com/case-studies/quest) [![Rady Children's Institute](https://events.tiledb.com/hs-fs/hubfs/RadyChildrensInstitute-h.png?width=190&height=68&name=RadyChildrensInstitute-h.png "Rady Children's Institute")](https://tiledb.com/case-studies/rady-children) [![Cellarity](https://events.tiledb.com/hs-fs/hubfs/Cellarity-h1.png?width=130&height=29&name=Cellarity-h1.png "Cellarity")](https://tiledb.com/case-studies/cellarity) [![PhenomicAI](https://events.tiledb.com/hs-fs/hubfs/PhenomicAI-h.png?width=180&height=33&name=PhenomicAI-h.png "PhenomicAI")](https://tiledb.com/case-studies/phenomic-ai) --- [![TileDB](https://events.tiledb.com/hubfs/TileDB__monogram.png) © TileDB, Inc. ](https://tiledb.com/) [![LinkedIn](https://events.tiledb.com/hubfs/LinkedIn%20logo_grey.png) ](https://www.linkedin.com/company/tiledb-inc/mycompany/) [![GitHub](https://events.tiledb.com/hubfs/GitHub_logo_grey.png) ](https://github.com/TileDB-Inc/TileDB) [![Twitter-X](https://events.tiledb.com/hubfs/Twitter-X_logo_grey.png) ](https://twitter.com/tiledb) ![](https://px.ads.linkedin.com/collect/?pid=2993961&fmt=gif)